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T15058 |
DBCO-amine
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DBCO-amine is a cleavable ADC linker used in antibody-drug conjugates (ADCs) synthesis[1]. |
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T17389 |
AMAS
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Others
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AMAS is a non-claevable heterobifunctional crosslinker with NHS ester and maleimide groups that enables covalent conjugation of amine- and sulfhydryl-containing molecules. |
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T4346 |
SPDB
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Others
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SPDB is a small fragment linked to DM4 conjugates. It conjugates to antibodies utilizing disulfide linkers: anti-EGFR-SPDB-DM4 has been widely used. |
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T22334 |
FMOC-3VVD-OH
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Others
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FMOC-3VVD-OH is an active chemical. |
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T18723 |
Succinic anhydride
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Others
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Succinic anhydride is a cyclic anhydride. Succinic anhydride acts as a nonclaevable ADC linker. Succinic anhydride can react with compound 4 to link the prodrug to an amine or hydroxy 1 group of a targeting polypeptide. |
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T15179 |
DTSSP Crosslinker
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Others
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DTSSP Crosslinker is a cleavable ADC linker and can be used to synthesize antibody-drug conjugates (ADCs). |
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T15176 |
DSS Crosslinker
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Others
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DSS Crosslinker is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).It is a homobifunctional crosslinker that is cell membrane permeable. DSS crosslinker has amine-reactive NHS esters a... |
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T16218 |
N-Boc-PEG5-bromide
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Others
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PROTAC Linker
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N-Boc-PEG5-bromide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. |
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T22278 |
BOC-Dap-NE
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Others
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Boc-Dap-NE used in the synthesis of antibody-drug conjugates (ADCs).It is a cleavable ADC linker |
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T15171 |
DSG Crosslinker
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Others
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DSG Crosslinker is a cleavable ADC linker used in antibody-drug conjugates (ADCs) synthesis. |
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T18868 |
Val-Cit
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Others
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Val-Cit is a cleavable ADC linker. Val-Cit is used in the synthesis of antibody-drug conjugates (ADCs). |
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T15175 |
DSP Crosslinker
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Others
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DSP Crosslinker is a cleavable ADC linker, used in antibody-drug conjugates (ADCs) synthesis[1]. |
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T8924 |
MFCD28987368
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Others
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MFCD28987368 is a degradable ADC linker that can be used in the synthesis of antibody coupled drugs (ADCs). |
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T17691 |
Boc-Val-Cit-OH
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Others
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Boc-Val-Cit-OH is a cleavable ADC linker used in antibody-drug conjugates (ADCs) synthesis. |
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T6741 |
SPDP
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SPDP Crosslinker |
Others
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SPDP is a short-chain crosslinker, which is used for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable (reducible) disulfide bonds with cysteine sulfhydryls. SPDP could ... |
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T17372 |
Ald-Ph-NHS ester
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Others
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Ald-Ph-NHS ester is a non-cleavable linker used in antibody-drug-conjugation (ADC). |
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T4678 |
Fmoc-Val-Cit-PAB
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Others
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Fmoc-Val-Cit-PAB is a linker for antibody-drug-conjugation (ADC). |
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T18308 |
MC-Gly-Gly-Phe
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MC-Gly-Gly-Phe is a cleavable linker. MC-Gly-Gly-Phe can be used for antibody-drug conjugates (ADC). |
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T17693 |
Boc-Val-Cit-PAB
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Others
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Boc-Val-Cit-PAB is a cleavable ADC linker. Boc-Val-Cit-PAB used in the synthesis of antibody-drug conjugates (ADCs). |
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T17213 |
Val-cit-PAB-OH
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Others
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Val-cit-PAB-OH is an ADC linker that is cleavable. |
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T17952 |
Fmoc-Gly-Gly-OH
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Others
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Fmoc-Gly-Gly-OH is a cleavable ADC linker. Fmoc-Gly-Gly-OH can be used in the synthesis of antibody-drug conjugates (ADCs). |
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T41312 |
Fmoc-Lys-OH hydrochloride
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PROTAC Linker
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Fmoc-Lys-OH hydrochloride is a alkyl-chain-based PROTAC linker. Fmoc-Lys-OH hydrochloride is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
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T7767 |
FMoc-Val-Cit-PAB-PNP
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Others
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Fmoc-Val-Cit-PAB-PNP is a linker for Antibody-Drug-Conjugation (ADC). |
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T18321 |
Mc-Val-Cit-PAB-Cl
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Others
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Mc-Val-Cit-PAB-Cl, a cleavable ADC linker, is utilized in the conjugation of MMAE and antibodies to produce compounds such as antibody-MC-vc-MMAE (e.g., anti-CD22-MC-VC-PABC-MMAE), which demonstrate cytotoxicity with IC5... |
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T17953 |
Fmoc-Gly-Gly-Phe-OtBu
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Others
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Fmoc-Gly-Gly-Phe-OtBu is a cleavable ADC linker. Fmoc-Gly-Gly-Phe-OtBu can be used in the synthesis of antibody-drug conjugates (ADCs). |
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T18540 |
Phe-Lys(Trt)-PAB
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Others
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Phe-Lys(Trt)-PAB is a cathepsin-cleavable linker utilized in the development of antibody-drug conjugates (ADCs)[1], serving as a crucial component for facilitating the release of therapeutic agents within targeted cells. |
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T18728 |
Sulfo-SMCC sodium
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Others
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Sulfo-SMCC sodium, a widely utilized non-cleavable, hetero-bifunctional crosslinker for antibody-drug conjugates (ADCs), features both N-hydroxysuccinimide (NHS) ester and maleimide groups. These functionalities enable i... |
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T16225 |
N-Hydroxysulfosuccinimide sodium
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N-Hydroxysulfosuccinimide sodium is a non-cleavable ADC linker used in antibody-drug conjugates (ADCs) synthesis. |
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T9783 |
Boc-C16-COOH
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PROTAC Linker
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Boc-C16-COOH is a alkyl-chain-based PROTAC linker. Boc-C16-COOH is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
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T17692 |
Boc-Val-Cit-PAB-PNP
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Others
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Boc-Val-Cit-PAB-PNP is a cleavable ADC linker used in antibody-drug conjugates (ADCs) synthesis. |
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T18318 |
MC-Val-Ala-PAB-PNP
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Others
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MC-Val-Ala-PAB-PNP is a cleavable ADC linker. MC-Val-Ala-PAB-PNP can be used in the synthesis of antibody-drug conjugates (ADCs). |
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T38953 |
Azido-C6-OH
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Azido-C6-OH is a cleavable ADC linker used to synthesize antibody-drug conjugates (ADCs). |
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T17679 |
Boc-NH-PEG4-CH2CH2NH2
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Others
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PROTAC Linker
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Boc-NH-PEG4-CH2CH2NH2 a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. |
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T14635 |
Bis-PEG3-NHS ester
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Others
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Bis-PEG3-NHS ester is a nonclaevable 3-unit PEG linker used in antibody-drug-conjugation (ADC). |
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T9785 |
20-(tert-Butoxy)-20-oxoicosanoic acid
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PROTAC Linker
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20-(tert-Butoxy)-20-oxoicosanoic acid is a alkyl-chain-based PROTAC linker. 20-(tert-Butoxy)-20-oxoicosanoic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
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T17946 |
Fmoc-Ala-Ala-Asn(Trt)-OH
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Others
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Fmoc-Ala-Ala-Asn(Trt)-OH is a cleavable linker vital in ADC synthesis. Fmoc-Ala-Ala-Asn(Trt)-OH joins cytotoxic drugs to antibodies, enabling precise delivery to cells or proteins. The cleavable nature ensures controlled... |
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T18479 |
NH-bis(C1-Boc)
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Others
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NH-bis(C1-Boc)is a uncleavable linker. NH-bis can be used for antibody-drug conjugates (ADC). |
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T18467 |
N3-C4-NHS ester
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Others
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N3-C4-NHS ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
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T9282 |
DBCO-C3-Acid
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DBCO-ACID |
Others
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DBCO acid 2 is a Click Chemistry intermidate used for antibody-drug conjugates. |
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T8667 |
MC-Gly-Gly-Phe-Gly
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DSN28369 |
Others
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MC-Gly-Gly-Phe-Gly (DSN28369) is a heterobifunctional linker, and useful to make antibody drug conjuate (ADC). |
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T16605 |
Propargyl-PEG3-acid
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PROTAC Linker
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Propargyl-PEG3-acid is a non-cleavable (3-unit PEG) ADC linker. Propargyl-PEG3-acid is also a PEG-based PROTAC linker used to synthesize 6-OHDA-PEG3-yne. 6-OHDA-PEG3-yne contains 6-OHDA and Propargyl-PEG3-acid[1]. |
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T15976 |
Mal-PEG1-NHS ester
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Others
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PROTAC Linker
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Mal-PEG1-NHS ester is a cleavable and PEG-based ADC linker used in the synthesis of antibody-drug conjugates (ADCs). It also is PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
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T18031 |
Hydroxy-PEG10-acid
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HO-PEG10-CH2CH2COOH |
Others
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PROTAC Linker
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Hydroxy-PEG10-acid (HO-PEG10-CH2CH2COOH) is a PEG-based PROTAC linker that can be used to synthesize PROTACs[1]. |
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T16315 |
NH2-PEG6-Boc
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PROTAC Linker
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NH2-PEG6-Boc is a PEG-based PROTAC linker that can be used in PROTAC synthesis[1]. NH2-PEG6-Boc is also a non-cleavable 6-unit PEG ADC linker used in antibody-drug conjugates(ADCs) synthesis[2]. |
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T9781 |
Boc-C14-COOH
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PROTAC Linker
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Boc-C14-COOH is a alkyl-chain-based PROTAC linker. Boc-C14-COOH is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
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T4289 |
Mc-Val-Ala-PAB
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Mc-Val-Ala-PAB |
Others
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AChR
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Mc-Val-Ala-PAB, an effective linker, is utilized in antibody-drug-conjugate (ADC). |
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T18529 |
PDEC-NB
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4-Nitrophenyl 2-(Pyridin-2-Yldisulfanyl)Ethyl Carbonate |
Others
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PDEC-NB (4-Nitrophenyl 2-(Pyridin-2-Yldisulfanyl)Ethyl Carbonate) is a disulfide cleavable linker. PDEC-NB can be used for the antibody-drug conjugate (ADC). |
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T17842 |
DOTA-NHS-ester
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Others
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DOTA-NHS-ester is a linker of affibody molecules for small animal PET, SPECT and CT. DOTA-NHS-ester can be used to label radiotherapeutic agents or imaging probes for tumor detection. |
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T17654 |
Boc-NH-C6-Br
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Others
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Boc-NH-C6-Br is a cleavable linker used for antibody-drug conjugates (ADC)[1]. |
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T17950 |
Fmoc-Asp-NH2
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Others
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Fmoc-Asp-NH2 is a cleavable ADC linker. Fmoc-Asp-NH2 can be used in the synthesis of antibody-drug conjugates (ADCs). |
